MITOCHONDRIA相关论文
Defects in mitochondria are responsible for various ge-netic and acquired diseases. Mitochondrial transplantation, a met......
Luteoloside protects the vascular endothelium against iron overload injury via the ROS/ADMA/DDAH Ⅱ/e
Iron overload injury is considered to be a part of blood stasis syndrome of arthralgia in traditional Chinese medicine.I......
Recommendations for the use of the acetaminophen hepatotoxicity model for mechanistic studies and ho
Acetaminophen(APAP)is a widely used analgesic and antipyretic drug,which is safe at ther-apeutic doses but can cause sev......
Alzheimer\'s disease(AD),the most prominent form of dementia in the elderly,has no cure.Strategies focused on the redu......
Genetic variation in apolipoprotein E(APOE)influences Alzheimer\'s disease(AD)risk.APOE e4 alleles are the strongest g......
Nitric oxide(NO)has emerged as an important signal molecule in plants,having myriad roles in plant devel-opment.In addit......
Mitochondria,double-membrane organelles,are known to participate in a variety of metabolic and signal transduction pathw......
Hepatic CDP-diacylglycerol synthase 2 deficiency causes mitochondrial dysfunction and promotes rapid
Nonalcoholic fatty liver disease (NAFLD) encompasses a spectrum of pathologies,ranging from steatosis to nonalcoholic st......
支气管哮喘(哮喘)是一种以不同程度的气流阻塞、气道高反应性和气道炎症为特点的复杂炎症性疾病。线粒体损伤及功能障碍是哮喘重要......
Inflammatory responses,including glial cell activation and peripheral immune cell infiltration,are involved in the patho......
Study on the protective effect of Tadehaginoside on the damage of endothelial cell mitochondria indu
ABSTRACT Objective: To investigate the protective effect of Tadehaginoside on vascular endothelial cell injury induced b......
目的:比较青蒿琥酯(Art)和扶正化瘀方治疗血吸虫病肝纤维化对线粒体自噬的影响。方法:将80只C57BL/6雌性小鼠随机分为健康组、感染......
Rictor/mTORC2 involves mitochondrial function in ES cells derived cardiomyocytes via mitochondrial C
Rictor is a key component of the mammalian target of rapamycin complex 2 (mTORC2) and is required for Akt phosphorylatio......
During normal aging, there is a decline in all physiological functions in the organism. One of the most affected organs ......
Mitochondrial dysfunctions in neurodegenerative diseases: role in disease pathogenesis, strategies f
Fundamental organelles that occur in every cell type with the exception of mammalerythrocytes, the mitochondria are requ......
Mitochondria play a multidimensional role in the function and the vitality of theneurological system. From the generatio......
Studies have shown that downregulation of nuclear-enriched autosomal transcript 1 (Neat1) may adversely affect the recov......
Stroke is considered a leading cause of mortality and neurological disability,which puts a huge burden on individuals an......
神经管畸形是在胚胎发育早期由于神经管闭合不全或障碍引起的一组严重的先天性畸形,包括无脑畸形、脑膜膨出和脊柱裂。线粒体是生物......
Mitochondria-targeting multi-metallic ZnCuO nanoparticles and IR780 for efficient photodynamic and p
Chemo-resistance has pushed cancer treatment to the boundary of failure.This challenge has encouraged scientists to look......
Bcl-xL is a pro-survival protein of the Bcl2 family found in the mitochondrial membrane. Bcl-xL supports growth, develop......
ObjeCtive:To study the antimalarial effects and mechanisms of artemisinin (Qinghaosu in Chinese,QHS) on mitochondda in m......
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Saeng-Kankunbi-Tang(生肝健脾汤)Protects Liver against Oxidative Damage through Activation of ERK/Nrf2 Pat
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Objective:To test the role of psoralidin in human liver cancer HepG2 cells in vitro.Methods:Cell viability was assessed ......
Objective:To investigate the effects of salvianolic acid A (SAA) on cardiomyocyte apoptosis and mitochondrial dysfunctio......
Enterovirus A71 (EV-A71) is one of the main causative agents of hand,foot and mouth disease (HFMD) and it also causes se......
Epididymal maturation is associated with the activation of a cAMP-induced tyrosine phosphorylation cascade,which is ulti......
Early apoptotic changes in human spermatozoa and their relationships with conventional semen paramet
Aim: To investigate whether early apoptotic changes in spermatozoa can be significant markers for sperm quality.Methods:......
The effects of long-term administration of tadalafil on STZ-induced diabetic rats with erectile dysf
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The effect of flutamide on the physical working capacity and activity of some of the key enzymes for
The aim of the study was to assess the effects of androgen receptor antagonists on the physical working capacity and act......
Two clinically relevant pressures of carbon dioxide pneumooperitoneum cause hepatic injury in a rabb
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Oxygen-boosted ATP-responsive chemotherapy and amplified ROS lethality induced by oxygen nanocarrier
Novel aptamer/doxorubicin-absorbed oxygen nanocarrier (A/D-ONC) is developed with polymeric core entrapping hemoglobin a......
Mitochondria content in different Tibetan pig muscle tissues and their association with the status o
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Mitochondria-targeted nanocarriers using hyperbranched polycations wrapped carbon nanotubes for augm
Photodynamic therapy (PDT),as a noninvasive therapeutic procedure,has been successfully applied to treat tumors and othe......
Dynamins are large superfamily GTPase proteins that are involved in various cellularpro-cesses including budding of tran......
Recent studies have reported that mitochondria serve as direct targets for cadmium-(Cd-)induced neuronal toxicity,which ......
Accumulated evidence showed that the apoptosis which is induced by ruthenium complexes play a key role in inhibiting the......
Ratiometric Fluorescence Imaging of Cellular Polarity:Mitochondrial Polarity Decreases in Cancer Cel
Polarity is an important parameter in chemistry and chemical technology.[1] In biological systems,especiallyat the cellu......
Introduction Enterovirns 71 (EV71) can cause hand, foot and mouth disease.The study aim to find the stereological charac......
Knockdown of NYGGF4(PID1)rescues insulin resistance and mitochondrial dysfunction induced by FCCP in
NYGGF4is a recently identified gene that is involved in obesity-associated insulin resistance.Previous data from this la......
Photodynamic therapy (PDT) based on the reactive oxygen species (ROS) produced by photosensitizers (PS) upon irradiation......